Dozens more refugees have left Manus Island for the United States despite coronavirus lockdowns and travel restrictions.
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The 35 men were joined by seven others brought to Australia for medical treatment.
But advocates are concerned for the health and job prospects of the 42 refugees as coronavirus runs rampant across America.
The men were transferred under a refugee resettlement deal struck between Canberra and Washington in 2016.
More than 700 refugees have gone to the US under the agreement, but hundreds more remain in Papua New Guinea and Nauru.
Australian Associated Press